Cenforce-D vs. ED & PE Medication Comparison Tool
Medication Selection
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Comparison Features
Feature | Cenforce-D | Viagra | Cialis | Levitra | Stendra | Priligy |
---|---|---|---|---|---|---|
Primary Indication | ED + PE | ED only | ED only | ED only | ED only | PE only |
Active Ingredients | Sildenafil 100 mg + Dapoxetine 60 mg | Sildenafil 50-100 mg | Tadalafil 10-20 mg | Vardenafil 10-20 mg | Avanafil 50 mg | Dapoxetine 30-60 mg |
Onset Time | 30-60 min (Sildenafil) + 1-3 h (Dapoxetine) | 30-60 min | 30-60 min (peak 2 h) - effects up to 36 h | 30-60 min | 15-30 min | 1-3 h |
Duration of Action | ≈4-5 h (ED) + 2-3 h (PE window) | ≈4-5 h | Up to 36 h | ≈4-5 h | ≈6 h | ≈2-3 h |
Typical Cost (US $) | $18-$22 | $12-$15 | $15-$20 | $14-$18 | $20-$25 | $30-$35 |
Common Side Effects | Headache, flushing, nausea, mild dizziness | Headache, facial flushing, dyspepsia | Back pain, muscle aches, headache | Headache, nasal congestion | Headache, nasal congestion, dizziness | Nausea, headache, dizziness |
Contraindications | Nitrates, severe CV disease, liver impairment | Same as above (no Dapoxetine) | Same as above (no Dapoxetine) | Same as above (no Dapoxetine) | Same as above (no Dapoxetine) | Concurrent use of MAOIs, severe cardiac disease |
Recommendation Engine
Based on your selections, here's a personalized recommendation:
If you’re weighing Cenforce-D against other options for erectile dysfunction (ED) and premature ejaculation (PE), you’ve come to the right place. This guide breaks down how the two‑active‑ingredient combo works, compares it to the most popular single‑drug and combo alternatives, and helps you decide which pill fits your needs.
TL;DR - Quick Takeaways
- Cenforce-D merges Sildenafil (for ED) and Dapoxetine (for PE) in a single tablet.
- Best for men who want a one‑stop solution for both issues.
- Single‑drug alternatives (Viagra, Cialis, Levitra, Stendra) treat only ED.
- Priligy (Dapoxetine alone) targets PE but does not help erection quality.
- Cost, onset time, and side‑effect profile differ widely; see the table below for a side‑by‑side view.
What Is Cenforce-D?
Cenforce-D is a tablet that combines 100mg Sildenafil citrate with 60mg Dapoxetine hydrochloride. It is marketed primarily in South‑Asian and Middle‑Eastern markets as a dual‑action remedy for men who experience both ED and PE. The Sildenafil component works by inhibiting phosphodiesterase‑5 (PDE‑5), allowing blood to flow into the penis. Dapoxetine, a short‑acting selective serotonin‑reuptake inhibitor (SSRI), extends the time to ejaculation without the long‑term sexual side effects typical of older SSRIs.
How the Two Ingredients Work Together
Sildenafil’s onset usually appears within 30‑60minutes and lasts up to 4‑5hours. Dapoxetine is taken 1‑3hours before sexual activity and provides a "window" of 2‑3hours to delay ejaculation. By bundling them, Cenforce‑D eliminates the need for two separate pills, reduces the chance of timing errors, and can improve compliance for men who struggle with the logistics of managing multiple medications.
Key Alternatives to Consider
Below are the most common alternatives that patients compare against Cenforce‑D:
- Viagra - 50mg or 100mg Sildenafil, ED‑only.
- Cialis - 10mg or 20mg Tadalafil, ED‑only, 24‑hour window.
- Levitra - 10mg or 20mg Vardenafil, ED‑only.
- Stendra - 50mg Avanafil, fast‑acting (15min).
- Priligy - 30mg or 60mg Dapoxetine, PE‑only.
- Kamagra (generic Sildenafil) - often sold in 100mg tablets, ED‑only.
Side‑by‑Side Comparison
Feature | Cenforce‑D | Viagra (Sildenafil) | Cialis (Tadalafil) | Levitra (Vardenafil) | Stendra (Avanafil) | Priligy (Dapoxetine) |
---|---|---|---|---|---|---|
Primary Indication | ED+PE | ED only | ED only | ED only | ED only | PE only |
Active Ingredients | Sildenafil100mg + Dapoxetine60mg | Sildenafil50‑100mg | Tadalafil10‑20mg | Vardenafil10‑20mg | Avanafil50mg | Dapoxetine30‑60mg |
Onset | 30‑60min (Sildenafil) + 1‑3h (Dapoxetine) | 30‑60min | 30‑60min (peak 2h) - effects up to 36h | 30‑60min | 15‑30min | 1‑3h |
Duration of Action | ≈4‑5h (ED) + 2‑3h (PE window) | ≈4‑5h | Up to 36h | ≈4‑5h | ≈6h | ≈2‑3h |
Typical Cost (US$) | ≈$18‑$22 per tablet (online sources) | ≈$12‑$15 | ≈$15‑$20 | ≈$14‑$18 | ≈$20‑$25 | ≈$30‑$35 |
Common Side Effects | Headache, flushing, nausea, mild dizziness | Headache, facial flushing, dyspepsia | Back pain, muscle aches, headache | Headache, nasal congestion | Headache, nasal congestion, dizziness | Nausea, headache, dizziness |
Contraindications | Nitrates, severe cardiovascular disease, liver impairment | Same as above (no Dapoxetine) | Same as above (no Dapoxetine) | Same as above (no Dapoxetine) | Same as above (no Dapoxetine) | Concurrent use of MAOIs, severe cardiac disease |

Decision Criteria - What Matters Most?
When you compare Cenforce‑D with the alternatives, ask yourself these questions:
- Do I need treatment for both ED and PE? If yes, a combo pill eliminates the hassle of two prescriptions.
- How quickly do I want the effect? Stendra is the fastest (15min), while Cialis gives the longest window (up to 36h).
- What’s my budget? Generic Sildenafil (Kamagra) and standard Viagra are often cheaper, but you’ll spend extra on a separate Dapoxetine if you need PE control.
- Am I on nitrates or have heart issues? All PDE‑5 inhibitors share the same contraindication; consult a physician before use.
- Do I prefer daily dosing? Cialis offers a low‑dose daily option (2.5mg) that maintains readiness without timing.
Best‑Fit Scenarios
Choose Cenforce‑D if you regularly face both erection difficulty and premature climax, and you want a single daily tablet that covers both. It’s also handy for occasional use when you can plan the timing of sexual activity.
Pick Viagra or Levitra when you only need a reliable, well‑studied ED solution and you’re comfortable swallowing a second pill for PE.
Opt for Cialis if you like spontaneity-its long half‑life means you don’t have to count minutes.
Consider Stendra for on‑the‑spot encounters where you have less than 30 minutes to act.
Use Priligy if the only issue is premature ejaculation and you have a separate ED medication already working for you.
Safety, Interactions, and Lifestyle Tips
All PDE‑5 inhibitors, including the Sildenafil in Cenforce‑D, can cause a sudden drop in blood pressure when combined with nitrates (e.g., nitroglycerin). Avoid heavy alcohol, as it may intensify dizziness or headache. Dapoxetine should be taken on an empty stomach for best absorption; a full meal can delay its effect by up to an hour.
If you have liver or kidney impairment, start at a lower dose (e.g., 50mg Sildenafil + 30mg Dapoxetine) and monitor tolerance. Women should never take these pills. For men over 65, doctors often recommend a reduced dose of Sildenafil to mitigate cardiovascular strain.
Cost, Availability, and Buying Tips
In 2025, Cenforce‑D is still sold mainly through online pharmacies that ship to the U.S., Canada, and Europe. Prices vary: a 10‑tablet pack usually runs $180‑$220. Look for reputable vendors that require a prescription verification step; the cheapest options often lack quality control.
Generic Sildenafil tablets are widely available at $0.80‑$1.20 each, while brand‑name Viagra costs $1.20‑$1.60 per tablet. Dapoxetine (Priligy) is prescription‑only in most Western markets and can be $8‑$12 per tablet.
When comparing total monthly costs, calculate the combined price of an ED pill plus a Dapoxetine pill versus the single price of Cenforce‑D. For many users, the combo saves $30‑$50 per month.
Frequently Asked Questions
Can I take Cenforce‑D with alcohol?
A small amount of alcohol (one drink) usually doesn’t cause issues, but heavy drinking can increase the risk of dizziness, low blood pressure, and reduced effectiveness. If you plan to drink, keep it moderate and give the medication at least an hour before.
How soon before sex should I take Cenforce‑D?
Take the tablet 1‑1.5hours before anticipated activity. The Sildenafil part starts working in 30‑60minutes, while Dapoxetine reaches peak levels around 2hours.
Is it safe to use Cenforce‑D every day?
Daily use is generally safe for healthy men, but the recommended dosing interval for Sildenafil is 24hours to avoid tolerance. Some doctors suggest a “drug‑holiday” of 2‑3 days each week.
Can I combine Cenforce‑D with other ED meds?
Never stack PDE‑5 inhibitors. Doing so dramatically raises the risk of a dangerous blood‑pressure drop. If Cenforce‑D isn’t enough, discuss dose adjustments with your doctor rather than adding another pill.
What should I do if I experience a painful erection?
A prolonged erection lasting more than 4hours (priapism) is a medical emergency. Seek immediate care; first‑line treatment is an injection of a vasodilator or oral medication to reverse the effect.
Bottom Line - Making the Choice
There’s no one‑size‑fits‑all answer, but the decision matrix is clear: if you need both ED and PE relief, the all‑in‑one nature of Cenforce‑D simplifies dosing and often cuts cost. If you only have ED, a single‑ingredient PDE‑5 inhibitor (Viagra, Cialis, or Stendra) provides more flexibility in timing and dose. For PE alone, Priligy remains the gold standard.
Always consult a healthcare professional before starting any medication, especially if you have cardiovascular disease, are on nitrates, or take other SSRIs. With the right choice, you’ll enjoy confidence in the bedroom without juggling multiple pills.
Eric Larson
Picture this: you’ve got ED and PE, and you’re juggling two pills-boom, Cenforce‑D drops in like a Swiss‑army knife!!! It hits the bedroom with a double‑strike, sildenafil for the lift and dapoxetine for the hold, saving you the hassle of timing two meds!!! The onset is a sweet combo-Sildenafil wakes up in 30‑60 minutes, dapoxetine rolls in about an hour later, so you’re covered for the whole session!!! No more guessing which pill to pop first, no more “wait, is it too late?”-just one tablet, two problems solved!!! And the price tag? Roughly $20 a pop, which often undercuts buying two separate prescriptions!!!