Aziderm Cream vs. Alternatives: Comparison Tool
Product Comparison
How to Choose Your Best Match
Based on your selected product and skin concerns, here are personalized recommendations:
- If you have severe acne, Aziderm Cream offers the highest concentration for fast results.
- For lightweight application, try Finacea or Paula’s Choice.
- For sensitive skin, Paula’s Choice includes soothing niacinamide.
- For budget-conscious users, The Ordinary provides excellent value.
- To combine treatments, consider alternating azelaic acid with benzoyl peroxide or salicylic acid.
Key Takeaways
- Aziderm Cream delivers 20% azelaic acid in a prescription‑strength cream, ideal for stubborn acne and rosacea.
- Finacea offers a similar 15% azelaic acid gel but is non‑prescription in some regions and feels lighter on the skin.
- The Ordinary’s 10% azelaic suspension is budget‑friendly, though lower concentration means slower results.
- Paula’s Choice 10% Azelaic Booster adds soothing niacinamide, making it a good option for sensitive skin.
- When choosing, consider concentration, formulation type, price, and any additional ingredients that match your skin concerns.
What is Aziderm Cream?
Aziderm Cream is a prescription‑strength 20% azelaic acid topical formulation that targets acne lesions and rosacea inflammation. It was launched in Australia in 2014 and quickly became a go‑to option for dermatologists treating moderate to severe acne.
The cream’s base is a semi‑rich emulsion that stays on the skin longer than gels, allowing the acid to work throughout the day. Because it’s a higher concentration, it can reduce both comedonal (blackheads) and inflammatory (red) lesions in as little as six weeks when used consistently.
How Aziderm Works
Azelaic acid is a dicarboxylic acid naturally found in grains like barley and wheat. It addresses three key pathways that cause acne:
- Killing skin‑friendly bacteria: It inhibits Propionibacterium acnes without disrupting the whole microbiome.
- Normalising keratinisation: By loosening the bonds between skin cells, it prevents the clogging of pores.
- Anti‑inflammatory action: It reduces the release of cytokines that cause redness and swelling.
These actions also help fade post‑inflammatory hyperpigmentation, making Aziderm a dual‑purpose treatment for acne‑prone skin.
Pros and Cons of Aziderm Cream
- Pros
- High 20% concentration delivers faster results.
- Creamy texture is soothing for dry or eczema‑prone skin.
- Clinically proven for both acne and rosacea.
- Prescription ensures you get medical guidance.
- Cons
- Requires a doctor’s script, adding an extra step.
- Cost can be higher than over‑the‑counter options.
- Potential for mild tingling or dryness during the first few weeks.
Top Alternatives to Aziderm Cream
If you’re looking for something over‑the‑counter, a different form factor, or a lower price point, these alternatives cover most needs.
Finacea (Azelaic Acid 15% Gel)
Finacea is a 15% azelaic acid gel approved for acne and rosacea, marketed as a non‑prescription option in many countries. Its gel base feels lightweight and dries quickly, which many users prefer in hot climates like Brisbane. The lower concentration means it’s gentler, reducing the chance of initial irritation.
The Ordinary Azelaic Acid Suspension 10%
The Ordinary Azelaic Acid Suspension 10% is an affordable, 10% azelaic acid powder‑in‑cream that targets blemishes and uneven tone. Because it’s a suspension, it may leave a faint white cast on deeper skin tones, but it’s a popular entry‑level product for people new to azelaic acid.
Paula’s Choice 10% Azelaic Acid Booster
Paula’s Choice 10% Azelaic Acid Booster is a lightweight serum that pairs azelaic acid with niacinamide and soothing botanical extracts. The added niacinamide helps reduce redness, making it a great choice for sensitive or barrier‑compromised skin.
Differin Gel (Adapalene 0.1%)
Differin Gel is a retinoid‑type acne treatment that works by normalising skin cell turnover, often used alongside azelaic acid. While not an azelaic product, many dermatologists recommend it as a complementary therapy for stubborn breakouts.
Benzoyl Peroxide 5% Cream
Benzoyl Peroxide 5% Cream is a classic acne medication that kills P. acnes bacteria through oxidation. It’s a strong antibacterial but can be drying, so pairing it with a moisturizing azelaic product can balance side effects.
Salicylic Acid 2% Lotion
Salicylic Acid 2% Lotion is a beta‑hydroxy acid formulation that exfoliates inside the pore to clear congestion. Ideal for oily, non‑comedogenic skin, it works well with azelaic acid for a two‑pronged approach.
Side‑by‑Side Comparison Table
| Product | Active ingredient | Concentration | Form | Typical price (AUD) | Best for |
|---|---|---|---|---|---|
| Aziderm Cream | Azelaic Acid | 20% | Cream | $70‑$85 (30g) | Severe acne, rosacea, sensitive skin needing extra moisture |
| Finacea | Azelaic Acid | 15% | Gel | $45‑$55 (30g) | People who prefer a lightweight feel and mild irritation risk |
| The Ordinary Azelaic Acid Suspension 10% | Azelaic Acid | 10% | Cream/Suspension | $9‑$12 (30g) | Budget‑conscious beginners, normal to oily skin |
| Paula’s Choice 10% Azelaic Booster | Azelaic Acid + Niacinamide | 10% | Serum | $35‑$42 (30ml) | Sensitive skin, those wanting added brightening benefits |
| Differin Gel | Adapalene | 0.1% | Gel | $30‑$40 (15g) | People needing stronger comedolysis, combined with azelaic |
| Benzoyl Peroxide 5% Cream | Benzoyl Peroxide | 5% | Cream | $12‑$18 (30g) | Highly inflamed, pus‑filled acne |
| Salicylic Acid 2% Lotion | Salicylic Acid | 2% | Lotion | $15‑$22 (100ml) | Oily skin, blackhead‑prone zones |
Choosing the Right Option for Your Skin
When you’re trying to decide, ask yourself three quick questions:
- Do I need a high concentration for fast results? If yes, Aziderm Cream tops the list.
- Is a lightweight texture a priority? Then Finacea’s gel or Paula’s Choice serum might feel more comfortable.
- What’s my budget? The Ordinary and generic benzoyl peroxide formulas keep the price under $20, but they may take longer to show improvement.
Another practical tip: rotate an azelaic product with benzoyl peroxide or salicylic acid only on alternate nights. This prevents over‑exfoliation while letting each ingredient do its job.
Potential Side Effects and How to Manage Them
Even the best‑tolerated azelaic items can cause initial tingling, dryness, or mild redness. Here’s a quick checklist to keep your skin happy:
- Start with a pea‑size amount and apply every other night for the first two weeks.
- Follow up with a fragrance‑free moisturizer - look for ceramides or hyaluronic acid.
- If you notice persistent burning, reduce frequency or switch to a lower concentration like The Ordinary.
- Always wear sunscreen: azelaic acid can make your skin more photosensitive.
Frequently Asked Questions
Can I use Aziderm Cream without a prescription?
In Australia, Aziderm is classified as a Schedule4 medication, so you need a doctor’s script. Some countries list it as over‑the‑counter, but you should still consult a dermatologist before starting.
How long does it take to see results?
Most users notice a reduction in red lesions within 4‑6 weeks. For discoloration fade‑out, give it 8‑12 weeks of consistent use.
Is azelaic acid safe during pregnancy?
Azelaic acid is generally considered low risk, but it’s best to discuss any topical treatment with your obstetrician before use.
Should I combine azelaic acid with retinoids?
Yes, but stagger the applications - azelaic in the morning, retinoid at night - to minimise irritation.
What’s the difference between a cream and a gel form?
Creams tend to be richer, providing extra barrier support for dry or eczema‑prone skin. Gels are water‑based, feel lighter, and dry faster - a preference for humid climates.
Next Steps
If you’ve pinpointed a product that matches your needs, schedule a quick chat with your dermatologist to confirm dosage and frequency. For over‑the‑counter options, start with a patch test on the jawline for three days. Track your skin’s response in a simple spreadsheet - note redness, breakouts, and any flaking. Adjust usage based on what the data tells you.
Remember, consistency beats occasional over‑use. Whichever route you choose, stick to a routine for at least eight weeks before deciding if it’s the right fit.
Christopher Eyer
While the guide meticulously lists alternatives, one might question whether the emphasis on prescription‑strength Aziderm is overstated given the comparable efficacy of lower‑dose formulations, especially for mild cases.